Domain III regulates N-type (CaV2.2) calcium channel closing kinetics
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چکیده
منابع مشابه
Domain III regulates N-type (CaV2.2) calcium channel closing kinetics.
Ca(V)2.2 (N-type) and Ca(V)1.2 (L-type) calcium channels gate differently in response to membrane depolarization, which is critical to the unique physiological functions mediated by these channels. We wondered if the source for these differences could be identified. As a first step, we examined the effect of domain exchange between N-type and L-type channels on activation-deactivation kinetics,...
متن کامل1 Domain III regulates N - type ( CaV 2 . 2 ) calcium channel closing kinetics 1
Domain III regulates N-type (CaV2.2) calcium channel closing kinetics 1 Viktor Yarotskyy, Guofeng Gao, Blaise Z Peterson, Keith S. Elmslie 2 3 Departments of Anesthesiology and Cellular and Molecular Physiology 4 Penn State College of Medicine, Penn State University, Hershey, PA 17033, and Department of 5 Pharmacology, Kirksville College of Osteopathic Medicine, AT Still University of Health 6 ...
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ژورنال
عنوان ژورنال: Journal of Neurophysiology
سال: 2012
ISSN: 0022-3077,1522-1598
DOI: 10.1152/jn.00993.2011